CXCL13/BCA1 Rekombinanter Antikörper

CXCL13/BCA1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250336E12

Kat-Nr. : 86564-1-PBS

Synonyme

Cxcl13, B lymphocyte chemoattractant, BCA1, Blc, CXC chemokine BLC

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  WB analysis using 86564-1-RR (same clone as 86564-1-PBS)

  Non-transfected and Cxcl13-transfected HEK-293T cell lysates were subjected to SDS PAGE followed by western blot with 86564-1-RR (Cxcl13 antibody) at a dilution of 1:5000, incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86564-1-PBS in a different storage buffer formulation.

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  WB analysis of Recombinant protein using 86564-1-RR (same clone as 86564-1-PBS)

  Mouse Cxcl13 Recombinant protein (cat no. Eg4484) were subjected to SDS PAGE followed by western blot with 86564-1-RR (Cxcl13 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86564-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

86564-1-PBS bindet in WB, Indirect ELISA CXCL13/BCA1 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CXCL13/BCA1 fusion protein Eg3331
• Vollständiger Name: chemokine (C-X-C motif) ligand 13
• Berechnetes Molekulargewicht: 12 kDa
• GenBank-Zugangsnummer: NM_018866
• Gene symbol: Cxcl13
• Gene ID (NCBI): 55985
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CXCL13 (C-X-C motif chemokine 13), originally named B-lymphocyte chemoattractant (BLC) or B cell-attracting chemokine 1 (BCA-1), is a homeostatic chemokine that is constitutively secreted by stromal cells in the B-cell follicles of secondary lymphoid tissues (e.g., spleen, lymph nodes, tonsils, and Peyer's patches). It plays a crucial role in orchestrating cell migration within distinct regions of secondary lymphoid organs, strongly attracting B lymphocytes (and, to a lesser extent, T cells and macrophages) via its receptor CXCR5 (originally named Burkitt's lymphoma receptor 1, BLR1). In addition to maintaining immune cell trafficking and lymphoid follicle development, CXCL13 is implicated in inflammatory and autoimmune diseases (e.g., systemic lupus erythematosus, rheumatoid arthritis) and tumor progression (e.g., multiple myeloma).