CXCL13/BCA1 Rekombinanter Antikörper

CXCL13/BCA1 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

250336E12

Kat-Nr. : 86564-1-RR

Synonyme

Cxcl13, B lymphocyte chemoattractant, BCA1, Blc, CXC chemokine BLC

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  WB analysis using 86564-1-RR

  Non-transfected and Cxcl13-transfected HEK-293T cell lysates were subjected to SDS PAGE followed by western blot with 86564-1-RR (Cxcl13 antibody) at a dilution of 1:5000, incubated at room temperature for 1.5 hours.

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  WB analysis of Recombinant protein using 86564-1-RR

  Mouse Cxcl13 Recombinant protein (cat no. Eg4484) were subjected to SDS PAGE followed by western blot with 86564-1-RR (Cxcl13 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Transfected with Mouse Cxcl13 Transfected HEK-293T cells, Recombinant protein

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

86564-1-RR bindet in WB, ELISA CXCL13/BCA1 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CXCL13/BCA1 fusion protein Eg3331
• Vollständiger Name: chemokine (C-X-C motif) ligand 13
• Berechnetes Molekulargewicht: 12 kDa
• GenBank-Zugangsnummer: NM_018866
• Gene symbol: Cxcl13
• Gene ID (NCBI): 55985
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CXCL13 (C-X-C motif chemokine 13), originally named B-lymphocyte chemoattractant (BLC) or B cell-attracting chemokine 1 (BCA-1), is a homeostatic chemokine that is constitutively secreted by stromal cells in the B-cell follicles of secondary lymphoid tissues (e.g., spleen, lymph nodes, tonsils, and Peyer's patches). It plays a crucial role in orchestrating cell migration within distinct regions of secondary lymphoid organs, strongly attracting B lymphocytes (and, to a lesser extent, T cells and macrophages) via its receptor CXCR5 (originally named Burkitt's lymphoma receptor 1, BLR1). In addition to maintaining immune cell trafficking and lymphoid follicle development, CXCL13 is implicated in inflammatory and autoimmune diseases (e.g., systemic lupus erythematosus, rheumatoid arthritis) and tumor progression (e.g., multiple myeloma).