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Cyclin D2 Monoklonaler Antikörper

Cyclin D2 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1A12A8

Kat-Nr. : 67048-1-PBS

Synonyme

CCND2, cyclin D, cyclin D2, G1/S specific cyclin D2, KIAK0002

Filter:
  • Western Blot (WB) analysis of various lysates using Cyclin D2 Monoclonal antibody (67048-1-Ig)

    WB analysis using 67048-1-Ig (same clone as 67048-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67048-1-Ig (CCND2 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67048-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of NIH/3T3 cells using Cyclin D2 Monoclonal antibody (67048-1-Ig)

    WB analysis of NIH/3T3 using 67048-1-Ig (same clone as 67048-1-PBS)

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 67048-1-Ig (CCND2 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67048-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

67048-1-PBS bindet in WB, Indirect ELISA Cyclin D2 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen Cyclin D2 fusion protein Ag25190
Vollständiger Name cyclin D2
Berechnetes Molekulargewicht 32 kDa
Beobachtetes Molekulargewicht 30 kDa
GenBank-ZugangsnummerBC010958
Gene symbol Cyclin D2
Gene ID (NCBI) 894
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CCND2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. CCND2 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. CCND2 has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. High level expression of CCND2 was observed in ovarian and testicular tumors.