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Cyclin E2 Rekombinanter Antikörper

Cyclin E2 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

243114A3

Kat-Nr. : 85803-3-PBS

Synonyme

CCNE2, CYCE2, Cyclin E, G1/S specific cyclin E2, G1/S-specific cyclin-E2

Filter:
  • Western Blot (WB) analysis of various lysates using Cyclin E2 Recombinant antibody (85803-3-RR)

    WB analysis using 85803-3-RR (same clone as 85803-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85803-3-RR (Cyclin E2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85803-3-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85803-3-PBS bindet in WB, Indirect ELISA Cyclin E2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Cyclin E2 fusion protein Ag2532
Vollständiger Name cyclin E2
Berechnetes Molekulargewicht 374 aa, 44 kDa
Beobachtetes Molekulargewicht 44 kDa
GenBank-ZugangsnummerBC020729
Gene symbol CCNE2
Gene ID (NCBI) 9134
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cyclin E2 (CCNE2) belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of cyclindependent kinases (CDKs). Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of cell cycle events. CCNE2 forms a complex with and functions as a regulatory subunit of CDK2 and has been shown to specifically interact with CIP/KIP family of CDK inhibitors. CCNE2 plays a role in cell cycle G1/S transition and its expression peaks at the G1-S phase. Whereas cyclin E1 is expressed in most proliferating normal and tumor cells, cyclin E2 levels are low or undetectable in nontransformed cells, and are elevated in tumor-derived cells.