Cyclophilin A Rekombinanter Antikörper

Cyclophilin A Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251706B11

Kat-Nr. : 86709-1-PBS

Synonyme

PPIA, Cyclosporin A binding protein, Cyclosporin A-binding protein, CYPA, CYPH



Geprüfte Anwendungen

Produktinformation

86709-1-PBS bindet in WB, Indirect ELISA Cyclophilin A und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Cyclophilin A fusion protein Ag1120
Vollständiger Name peptidylprolyl isomerase A (cyclophilin A)
Berechnetes Molekulargewicht 18 kDa
Beobachtetes Molekulargewicht 18 kDa
GenBank-ZugangsnummerBC005320
Gene symbol PPIA
Gene ID (NCBI) 5478
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cyclophilin A, also named as PPIA and Rotamase A, belongs to the cyclophilin-type PPIase family and PPIase A subfamily. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity. PPIA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.