Cyclophilin A Rekombinanter Antikörper
Cyclophilin A Rekombinant Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
251706B11
Kat-Nr. : 86709-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
86709-1-PBS bindet in WB, Indirect ELISA Cyclophilin A und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Rekombinant |
| Typ | Antikörper |
| Immunogen | Cyclophilin A fusion protein Ag1120 |
| Vollständiger Name | peptidylprolyl isomerase A (cyclophilin A) |
| Berechnetes Molekulargewicht | 18 kDa |
| Beobachtetes Molekulargewicht | 18 kDa |
| GenBank-Zugangsnummer | BC005320 |
| Gene symbol | PPIA |
| Gene ID (NCBI) | 5478 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Cyclophilin A, also named as PPIA and Rotamase A, belongs to the cyclophilin-type PPIase family and PPIase A subfamily. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA forms a trimolecular complex with cyclophilin and calcineurins to inhibit calcineurin phosphatase activity. PPIA is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein and is crucial for efficient viral replication.

