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Cyclophilin E Rekombinanter Antikörper

Cyclophilin E Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250296A6

Kat-Nr. : 85952-1-PBS

Synonyme

PPIE, Cyclophilin 33, Cyclophilin-33, CYP 33, CYP33

Filter:
  • Western Blot (WB) analysis of various lysates using Cyclophilin E Recombinant antibody (85952-1-RR)

    WB analysis using 85952-1-RR (same clone as 85952-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85952-1-RR (Cyclophilin E antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85952-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85952-1-RR

    Affinity and Kinetic Characterization of 85952-1-RR

    Biolayer interferometry (BLl) kinetic assays of 85952-1-RR against Human Cyclophilin E were performed. The affinity constant is 58.2 nM.

Geprüfte Anwendungen

Produktinformation

85952-1-PBS bindet in WB, Indirect ELISA Cyclophilin E und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Cyclophilin E fusion protein Ag7603
Vollständiger Name peptidylprolyl isomerase E (cyclophilin E)
Berechnetes Molekulargewicht 33 kDa
Beobachtetes Molekulargewicht 33 kDa
GenBank-ZugangsnummerBC004898
Gene symbol Cyclophilin E
Gene ID (NCBI) 10450
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cyclophilin E (CypE), also known as Cyclophilin-33, Rotamase E, CYP33, PPIE, is an enzyme which belongs to the cyclophilin-type PPIase family of PPIase E subfamily (PMID: 15998457). Cyclophilin E negatively regulates influenza virus replication and transcription occurs by impairing the formation of the vRNP (PMID: 21887220). Additionally, Cyclophilin E plays an important role in osteoblast differentiation as a positive regulator by increasing the transcriptional activity of Runx2 (PMID: 37947627).