Cytokeratin 13 Monoklonaler Antikörper

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• KD/KO Validated

Cytokeratin 13 Monoklonal Antikörper für IF-P

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Ratte

Anwendung

IF-P

Konjugation

CoraLite® Plus 488 Fluorescent Dye

Publikationen(1)

CloneNo.

1E10G2

Kat-Nr. : CL488-66684

Synonyme

KRT13, Cytokeratin,Keratin, ck17, CK-13, CK13

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  IF Staining of human cervical cancer using CL488-66684

  Immunofluorescent analysis of (4% PFA) fixed human cervical cancer tissue using CoraLite® Plus 488 Cytokeratin 13 antibody (CL488-66684, Clone: 1E10G2 ) at dilution of 1:100.

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  IF Staining of human cervical cancer using CL488-66684

  Immunofluorescent analysis of (4% PFA) fixed human cervical cancer tissue using CoraLite® Plus 488 Cytokeratin 13 antibody (CL488-66684, Clone: 1E10G2 ) at dilution of 1:100.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IF-P: humanes Zervixkarzinomgewebe

Empfohlene Verdünnung

• Immunfluoreszenz (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• IF: See 1 publications below

Produktinformation

CL488-66684 bindet in IF-P Cytokeratin 13 und zeigt Reaktivität mit human, Ratten

• Getestete Reaktivität: human, Ratte
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Cytokeratin 13 fusion protein Ag0217
• Vollständiger Name: keratin 13
• Berechnetes Molekulargewicht: 50 kDa
• Beobachtetes Molekulargewicht: 50 kDa
• GenBank-Zugangsnummer: BC002661
• Gene symbol: Cytokeratin 13
• Gene ID (NCBI): 3860
• Konjugation: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 493 nm / 522 nm
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA
• Lagerungsbedingungen: Bei -20°C lagern. Vor Licht schützen. Nach dem Versand ein Jahr stabil. Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9-K23, and the hair keratins Ha1-Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1-K8, and the hair keratins, Hb1-Hb6. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. The Keratin 13 (KRT13) gene encodes a type I acidic keratin which is expressed in the differentiated cells of non-cornified stratified squamous epithelia.

Publikationen

Species	Application	Title
human	IF	Int J Mol Sci; Shedding Light on Viral Shedding: Novel Insights into Nuclear Assembly, Cytoplasmic Transformation and Extracellular Vesicle Release of the BK Virus; Authors - Daniela Gerges