DCUN1D3 Polyklonaler Antikörper

DCUN1D3 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 26356-1-AP

Synonyme

44M2.4, DCN1 like protein 3, DCUN1D3

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  WB analysis of MCF-7 using 26356-1-AP

  MCF-7 cells were subjected to SDS PAGE followed by western blot with 26356-1-AP (DCUN1D3 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  WB analysis of A549 using 26356-1-AP

  A549 cells were subjected to SDS PAGE followed by western blot with 26356-1-AP (DCUN1D3 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: MCF-7-Zellen, A549-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

26356-1-AP bindet in WB, ELISA DCUN1D3 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: DCUN1D3 fusion protein Ag23730
• Vollständiger Name: DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
• Beobachtetes Molekulargewicht: 34 kDa
• GenBank-Zugangsnummer: BC040442
• Gene symbol: DCUN1D3
• Gene ID (NCBI): 123879
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DCUN1D3, also named as SCCRO3, is proposed to function as a tumor suppressor. DCUN1D3 antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane (PubMed:25349211). When overexpressed in transformed cells, DCUN1D3 may promote mesenchymal to epithelial-like changes and inhibit colony formation in soft agar (PubMed:25349211).