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DDX11 Polyklonaler Antikörper

DDX11 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13047-1-PBS

Synonyme

ATP-dependent DNA helicase DDX11, CHL1-related protein 1, DDX 11, DEAD/H-box protein 11, EC:3.6.4.12

Filter:
  • Western Blot (WB) analysis of various lysates using DDX11 Polyclonal antibody (13047-1-AP)

    WB analysis using 13047-1-AP (same clone as 13047-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13047-1-AP (DDX11 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13047-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

13047-1-PBS bindet in WB, Indirect ELISA DDX11 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen DDX11 fusion protein Ag3666
Vollständiger Name DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae)
Berechnetes Molekulargewicht 970 aa, 108 kDa
Beobachtetes Molekulargewicht102-108 kDa
GenBank-ZugangsnummerBC011264
Gene symbol DDX11
Gene ID (NCBI) 1663
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DDX11 (DEAD/H-box helicase 11), also known as hCHLR1, KRG-2, is a member of the DExD/H (Asp-Glu-x-Asp/His)-box helicase family containing DNA helicase with roles in DNA replication and sister chromatid cohesion establishment, and general chromosome architecture (PMID: 33802088). DDX11 encodes an iron-sulfur cluster DNA helicase required for development, mutated, and overexpressed in cancers (PMID: 33879618). DDX11 is also a positive regulator of the RIG-I-mitochondrial antiviral signaling protein (MAVS)-mediated signaling pathways (PMID: 39470258).