DLGAP3 Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

DLGAP3 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus und mehr (1)

Anwendung

WB, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(3)

Kat-Nr. : 55056-1-AP

Synonyme

DAP 3, DAP3, DAP-3, Disks large-associated protein 3, PSD 95/SAP90 binding protein 3

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  WB analysis using 55056-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 55056-1-AP (DLGAP3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse brain using 55056-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 55056-1-AP (DLGAP3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: SH-SY5Y-Zellen, Maushirngewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 3 publications below
• IF: See 1 publications below

Produktinformation

55056-1-AP bindet in WB, IF, ELISA DLGAP3 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: discs, large (Drosophila) homolog-associated protein 3
• Berechnetes Molekulargewicht: 106 kDa
• Beobachtetes Molekulargewicht: 106-120 kDa
• GenBank-Zugangsnummer: NM_001080418
• Gene symbol: DLGAP3
• Gene ID (NCBI): 58512
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DLGAP3, also named as DAP3, belongs to the SAPAP family. It may play a role in the molecular organization of synapses and neuronal cell signaling. DLGAP3 could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. It may induce enrichment of PSD-95/SAP90 at the plasma membrane. The antibody has no cross reaction to other DLGAP members.

Publikationen

Species	Application	Title
rat	WB	Biol Psychiatry; Metabotropic Glutamate Receptor and Fragile X Signaling in a Female Model of Escalated Aggression.; Authors - Laura E Been
mouse,human	WB,IF	Cell Death Dis; SAPAP3 regulates epileptic seizures involving GluN2A in post-synaptic densities.; Authors - Yanke Zhang ; KD Validated
mouse	WB	Nat Neurosci; Neuronal activity rapidly reprograms dendritic translation via eIF4G2:uORF binding; Authors - Ezgi Hacisuleyman