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DLST Polyklonaler Antikörper

DLST Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31174-1-PBS

Synonyme

DLTS, OGDC E2

Filter:
  • Western Blot (WB) analysis of various lysates using DLST Polyclonal antibody (31174-1-AP)

    WB analysis using 31174-1-AP (same clone as 31174-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31174-1-AP (DLST antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31174-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using DLST Polyclonal antibody (31174-1-AP)

    IF Staining of HeLa using 31174-1-AP (same clone as 31174-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using DLST antibody (31174-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 31174-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31174-1-PBS bindet in WB, IF/ICC, Indirect ELISA DLST und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen DLST fusion protein Ag34753
Vollständiger Name dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
Berechnetes Molekulargewicht 49 kDa
Beobachtetes Molekulargewicht40 kDa, 49 kDa
GenBank-ZugangsnummerBC001922
Gene symbol DLST
Gene ID (NCBI) 1743
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DLST (Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex) ) is the E2 transferase of α-ketoglutarate dehydrogenase complex (KGDHC) that regulates the irreversible conversion of α-ketoglutarate to succinyl-CoA in the TCA cycle.RNAi knockdown of DLST led to decreased cell viability and induction of apoptosis in human T-ALL cell lines. High DLST expression predicts poor overall and recurrencefree survival among TNBC patients (PMID: 26876595, 34785772). DLST has two isoforms of 40 kDa, 49 kDa.