DLX6 Rekombinanter Antikörper

DLX6 Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250408B4

Kat-Nr. : 85946-1-PBS

Synonyme

Homeobox protein DLX-6

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  WB analysis using 85946-1-RR (same clone as 85946-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85946-1-RR (DLX6 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85946-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse embryo using 85946-1-RR (same clone as 85946-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse embryo tissue slide using 85946-1-RR (DLX6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85946-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse embryo using 85946-1-RR (same clone as 85946-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse embryo tissue slide using 85946-1-RR (DLX6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85946-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 85946-1-RR

  Biolayer interferometry (BLl) kinetic assays of 85946-1-RR against Human DLX6 were performed. The affinity constant is 5.65 nM.

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Geprüfte Anwendungen

Produktinformation

85946-1-PBS bindet in WB, IHC, Indirect ELISA DLX6 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: DLX6 fusion protein Ag19724
• Vollständiger Name: distal-less homeobox 6
• Berechnetes Molekulargewicht: 175 aa, 20 kDa
• Beobachtetes Molekulargewicht: 32 kDa
• GenBank-Zugangsnummer: BC069363
• Gene symbol: DLX6
• Gene ID (NCBI): 1750
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Distal-less homeobox 6 (DLX6) has been reported to play important roles in the development of craniofacial structures, inner ear, limb, and brain. DLX6 was significantly highly expressed in oral cancer tissues in The Cancer Genome Atlas database. DLX6 promotes cell proliferation and suppresses cell apoptosis in oral cancer cells. EGFR-CCND1 pathway might be the potential mechanism participating in the regulating axis (PMID: 33215805).