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DMRT1 Polyklonaler Antikörper

DMRT1 Polyklonal Antikörper für WB, IF-P, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IF-P, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 28149-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using DMRT1 Polyclonal antibody (28149-1-AP)

    WB analysis using 28149-1-AP (same clone as 28149-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28149-1-AP (DMRT1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28149-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of mouse testis tissue using DMRT1 Polyclonal antibody (28149-1-AP)

    IF Staining of mouse testis using 28149-1-AP (same clone as 28149-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse testis tissue using DMRT1 antibody (28149-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 28149-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

28149-1-PBS bindet in WB, IF-P, Indirect ELISA DMRT1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen DMRT1 fusion protein Ag28006
Vollständiger Name doublesex and mab-3 related transcription factor 1
Berechnetes Molekulargewicht 39 kDa
Beobachtetes Molekulargewicht39 kDa
GenBank-ZugangsnummerBC040847
Gene symbol DMRT1
Gene ID (NCBI) 1761
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DMRT1, also named DMT1, belongs to the DMRT family. DMRT1 is one of the most conserved transcription factors in a variety of species and is involved in sex determination and germ cell differentiation. DMRT1 prevents the sexual switch from male to female, represses pluripotency, and balances mitosis versus meiosis. DMRT1 also maintains spermatogenesis and replenishes mGSCs by collaborating with Plzf and Sal-like protein 4 (PMID: 33420764). DMRT1 has 3 isoforms with the molecular mass of 18, 29, and 39 kDa.