DNAJC17 Polyklonaler Antikörper
DNAJC17 Polyklonal Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 31580-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
31580-1-PBS bindet in WB, Indirect ELISA DNAJC17 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | DNAJC17 fusion protein Ag35992 |
| Vollständiger Name | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| Berechnetes Molekulargewicht | 304 aa, 35 kDa |
| Beobachtetes Molekulargewicht | 34 kDa |
| GenBank-Zugangsnummer | BC000048 |
| Gene symbol | DNAJC17 |
| Gene ID (NCBI) | 55192 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
DnaJ proteins, also known as Hsp40, are a set of highly conserved proteins typically acting as co-factors of Hsp70 molecular chaperones. Based on their domain architecture, DNAJ is classified into three different groups (A, B, and C). DNAJC17 belongs to group C, bearing the J domain at its N-terminal region and an RNA recognition motif (RRM) located at the protein C-terminu. DNAJC17 is a susceptibility gene for congenital hypothyroidism and demonstrated its wide expression in mice since early embryogenesis, in which it plays an essential role in pre-implantation stages (PMID: 29773831).

