DNAJC17 Polyklonaler Antikörper

DNAJC17 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31580-1-PBS

Synonyme



Geprüfte Anwendungen

Produktinformation

31580-1-PBS bindet in WB, Indirect ELISA DNAJC17 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen DNAJC17 fusion protein Ag35992
Vollständiger Name DnaJ (Hsp40) homolog, subfamily C, member 17
Berechnetes Molekulargewicht 304 aa, 35 kDa
Beobachtetes Molekulargewicht 34 kDa
GenBank-ZugangsnummerBC000048
Gene symbol DNAJC17
Gene ID (NCBI) 55192
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DnaJ proteins, also known as Hsp40, are a set of highly conserved proteins typically acting as co-factors of Hsp70 molecular chaperones. Based on their domain architecture, DNAJ is classified into three different groups (A, B, and C). DNAJC17 belongs to group C, bearing the J domain at its N-terminal region and an RNA recognition motif (RRM) located at the protein C-terminu. DNAJC17 is a susceptibility gene for congenital hypothyroidism and demonstrated its wide expression in mice since early embryogenesis, in which it plays an essential role in pre-implantation stages (PMID: 29773831).