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DOCK1 Monoklonaler Antikörper

DOCK1 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1C3F12

Kat-Nr. : 67296-1-PBS

Synonyme

ced5, dedicator of cytokinesis 1, DOCK1, DOCK180

Filter:
  • Western Blot (WB) analysis of various lysates using DOCK1 Monoclonal antibody (67296-1-Ig)

    WB analysis using 67296-1-Ig (same clone as 67296-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67296-1-Ig (DOCK1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67296-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using DOCK1 Monoclonal antibody (67296-1-Ig)

    WB analysis using 67296-1-Ig (same clone as 67296-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67296-1-Ig (DOCK1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67296-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

67296-1-PBS bindet in WB, Indirect ELISA DOCK1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen DOCK1 fusion protein Ag18069
Vollständiger Name dedicator of cytokinesis 1
Berechnetes Molekulargewicht 1865 aa, 215 kDa
Beobachtetes Molekulargewicht 215 kDa
GenBank-ZugangsnummerBC146857
Gene symbol DOCK1
Gene ID (NCBI) 1793
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DOCK1, also named as DOCK180, belongs to the DOCK family. It is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. DOCK1 functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1