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DOCK4 Polyklonaler Antikörper

DOCK4 Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27151-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of HEK-293T cells using DOCK4 Polyclonal antibody (27151-1-AP)

    WB analysis of HEK-293T using 27151-1-AP (same clone as 27151-1-PBS)

    HEK-293T cells were subjected to SDS PAGE followed by western blot with 27151-1-AP (DOCK4 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27151-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using DOCK4 Polyclonal antibody (27151-1-AP)

    IF Staining of HeLa using 27151-1-AP (same clone as 27151-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using 27151-1-AP (DOCK4 antibody) at dilution of 1:50 and CoraLite488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27151-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27151-1-PBS bindet in WB, IF/ICC, Indirect ELISA DOCK4 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen DOCK4 fusion protein Ag25946
Vollständiger Name dedicator of cytokinesis 4
Berechnetes Molekulargewicht 2011 aa, 230 kDa
Beobachtetes Molekulargewicht 225 kDa
GenBank-ZugangsnummerBC117689
Gene symbol DOCK4
Gene ID (NCBI) 9732
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DOCK4, originally identified as a product of a gene which is deleted during tumor progression, is a member of DOCK180 family proteins. Dock4 has been found recently to be associated with several neuropsychiatric diseases, including autism, dyslexia, and schizophrenia. Multiple studies in fibroblasts then confirmed that Dock4 is capable of controlling cell migration by transducing several upstream signals, such as Wnt, platelet-derived growth factor, and RhoG, toward activation of Rac1. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers.