• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

DOPA decarboxylase/DDC Rekombinanter Antikörper

DOPA decarboxylase/DDC Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

243125A1

Kat-Nr. : 85811-2-PBS

Synonyme

DDC, DOPA decarboxylase, AADC, Aromatic-L-amino-acid decarboxylase, EC:4.1.1.28

Filter:
  • Western Blot (WB) analysis of various lysates using DOPA decarboxylase/DDC Recombinant antibody (85811-2-RR)

    WB analysis using 85811-2-RR (same clone as 85811-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85811-2-RR (DOPA decarboxylase/DDC antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85811-2-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85811-2-PBS bindet in WB, Indirect ELISA DOPA decarboxylase/DDC und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen DOPA decarboxylase/DDC fusion protein Ag0219
Vollständiger Name dopa decarboxylase (aromatic L-amino acid decarboxylase)
Berechnetes Molekulargewicht 54 kDa
Beobachtetes Molekulargewicht 48-50 kDa
GenBank-ZugangsnummerBC008366
Gene symbol DOPA decarboxylase
Gene ID (NCBI) 1644
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DOPA decarboxylase (DDC), also known as aromatic l-amino acid decarboxylase, belongs to the pyridoxal-dependent aminotransferase superfamily. DDC is an enzyme that converts levodopa into dopamine14, the latter being severely depleted in LBD due to the loss of dopaminergic neurons in the substantia nigra (PMID: 3374198, PMID: 28100251). DDC catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. DDC is the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). Researches showed that Ddc is only one of the enzymes in the biosynthetic pathways for bioamines and catecholamines.