DPP4/CD26 Rekombinanter Antikörper

DPP4/CD26 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

242823A9

Kat-Nr. : 98356-1-PBS

Synonyme

Dipeptidyl peptidase IV, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase 4 membrane form, Dipeptidyl peptidase 4, CD26

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  FC experiment of mouse splenocytes using 98356-1-RR (same clone as 98356-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.125 ug Anti-Mouse DPP4/CD26 Rabbit RecAb (98356-1-RR, Clone:242823A9) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-conjugated Goat Anti-Rabbit IgG. Cells were then stained with APC Anti-Human CD3. Cells were not fixed. This data was developed using the same antibody clone with 98356-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse splenocytes using 98356-1-RR (same clone as 98356-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.125 ug Anti-Mouse DPP4/CD26 Rabbit RecAb (98356-1-RR, Clone: 242823A9) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were not fixed. This data was developed using the same antibody clone with 98356-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98356-1-PBS bindet in FC DPP4/CD26 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: dipeptidylpeptidase 4
• Berechnetes Molekulargewicht: 87 kDa
• GenBank-Zugangsnummer: NM_010074.3
• Gene symbol: Dpp4
• Gene ID (NCBI): 13482
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CD26, also known as DPP4 (dipeptidyl peptidase-4), is a 110 kDa type II cell-surface glycoprotein widely expressed on T cells, activated B cells, activated NK cells and myeloid cells as well as on epithelial cells, fibroblasts, mesothelium, and endothelial cells of a variety of tissues (PMID:33777580; 26919392). It has ecto-enzyme activity in its extracellular domain and cleaves amino-terminal dipeptides with either L-proline or L-alanine at the penultimate position (PMID: 9553764). CD26 plays roles in diverse biological processes such as immunoregulation, glucose homeostasis, and tumorigenesis (PMID: 33777580).