DPYD Polyklonaler Antikörper

DPYD Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25690-1-PBS

Synonyme

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  WB analysis of mouse liver using 25690-1-AP (same clone as 25690-1-PBS)

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 25690-1-AP (DPYD antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25690-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

25690-1-PBS bindet in WB, Indirect ELISA DPYD und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: DPYD fusion protein Ag20885
• Vollständiger Name: dihydropyrimidine dehydrogenase
• Berechnetes Molekulargewicht: 1025 aa, 111 kDa
• Beobachtetes Molekulargewicht: 111 kDa
• GenBank-Zugangsnummer: BC008379
• Gene symbol: DPYD
• Gene ID (NCBI): 1806
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy.