DR3 Polyklonaler Antikörper

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DR3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55397-1-PBS

Synonyme

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  WB analysis of PC-3 using 55397-1-AP (same clone as 55397-1-PBS)

  WB result of DR3 antibody (55397-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-DR3 transfected PC-3 cells. This data was developed using the same antibody clone with 55397-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 55397-1-AP (same clone as 55397-1-PBS)

  PC-3 cells were subjected to SDS PAGE followed by western blot with 55397-1-AP (DR3 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55397-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse spleen using 55397-1-AP (same clone as 55397-1-PBS)

  mouse spleen tissue were subjected to SDS PAGE followed by western blot with 55397-1-AP (DR3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55397-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse thymus using 55397-1-AP (same clone as 55397-1-PBS)

  mouse thymus tissue were subjected to SDS PAGE followed by western blot with 55397-1-AP (DR3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55397-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

55397-1-PBS bindet in WB, Indirect ELISA DR3 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: tumor necrosis factor receptor superfamily, member 25
• Berechnetes Molekulargewicht: 46 kDa
• Beobachtetes Molekulargewicht: 52 kDa, 17-20 kDa
• GenBank-Zugangsnummer: NM_003790
• Gene symbol: DR3
• Gene ID (NCBI): 8718
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TNFRSF25, also named as APO3, DDR3, DR3, TNFRSF12, WSL, WSL1, LARD, TRAMP and AIR, is a receptor for TNFSF12/APO3L/TWEAK. TNFRSF25 interacts directly with the adapter TRADD. It mediates activation of NF-kappa-B and induces apoptosis. TNFRSF25 may play a role in regulating lymphocyte homeostasis. It is constitutively and highly expressed by CD4(+)FoxP3(+) Tregs. This antibody can recognize all the isoform of TNFRSF25.