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DR5 Rekombinanter Antikörper

DR5 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241847B8

Kat-Nr. : 84524-4-PBS

Synonyme

Tnfrsf10b, MK, Killer, Death receptor 5, CD262

Filter:
  • Western Blot (WB) analysis of NIH/3T3 cells using DR5 Recombinant antibody (84524-4-RR)

    WB analysis of NIH/3T3 using 84524-4-RR (same clone as 84524-4-PBS)

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 84524-4-RR (DR5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84524-4-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

84524-4-PBS bindet in WB, Indirect ELISA DR5 und zeigt Reaktivität mit Maus

Getestete Reaktivität Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen FusionProtein
Vollständiger Name tumor necrosis factor receptor superfamily, member 10b
Berechnetes Molekulargewicht42kDa
Beobachtetes Molekulargewicht50 kDa
GenBank-ZugangsnummerNM_020275.4
Gene symbol DR5
Gene ID (NCBI) 21933
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DR5, also known as CD262, TNFRSF10B, TRAILR2, TRICK2 and KILLER, is a widely expressed single-pass type I membrane protein belonging to the tumour necrosis factor receptor superfamily (TNFRSF). It is a receptor for TNF-related apoptosis-inducing ligand (TRAIL), which is a member of the tumor necrosis factor (TNF) family of cytokines and induces apoptosis in a wide variety of cells (PMID: 9311998). DR5 contains two extracellular cysteine-rich repeats, typical for TNF receptor (TNFR) family members, and a cytoplasmic death domain (DD), through which DR5 is capable to transmit the apoptotic signal (PMID: 9311998; 20531300).