DRD1 Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

DRD1 Polyklonal Antikörper für WB, IF-Fro, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF-Fro, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17934-1-PBS

Synonyme

D(1A) dopamine receptor, DADR, Dopamine D1 receptor, dopamine receptor D1

---

• 

  WB analysis of mouse brain using 17934-1-AP (same clone as 17934-1-PBS)

  37°C incubated mouse brain tissue were subjected to SDS PAGE followed by western blot with 17934-1-AP (DRD1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17934-1-PBS in a different storage buffer formulation.

• 

  IF Staining of mouse brain using 17934-1-AP (same clone as 17934-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed frozen OCT-embedded mouse brain tissue using DRD1 antibody (17934-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 17934-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

17934-1-PBS bindet in WB, IF-Fro, ELISA DRD1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: DRD1 fusion protein Ag12366
• Vollständiger Name: dopamine receptor D1
• Berechnetes Molekulargewicht: 446 aa, 49 kDa
• Beobachtetes Molekulargewicht: 50-75 kDa
• GenBank-Zugangsnummer: BC074978
• Gene symbol: DRD1
• Gene ID (NCBI): 1812
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Dopamine is a neurotransmitter that plays a crucial role in physical and mental health, such as cardiovascular, hormonal, renal, and central nervous systems (PMID: 29220802). Five subtypes of mammalian dopamine receptors are grouped into two classes, the D1- and D2-like classes. The D1-like class includes D1 and D5 receptors whereas the D2-like class includes D2, D3, D4 subtypes (PMID: 9457173). Dopamine receptor D1 (DRD1) is the most abundant form of dopamine receptor in the central nervous system. DRD1 stimulates adenylate cyclase, modulates D2 receptor activity, regulates neuron growth and differentiation, and mediates several behavioral responses (PMID: 1977312). DRD1 has a calculated molecular weight of 49 kDa, larger apparent molecular weight of 60-80 kDa may be due to glycosylation (PMID: 1281547; 23821371).