Desmocollin 2 Monoklonaler Antikörper
Desmocollin 2 Monoklonal Antikörper für WB, IF-P, ELISA
Wirt / Isotyp
Maus / IgG2a
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, IF-P, ELISA
Konjugation
Unkonjugiert
CloneNo.
1H8G1
Kat-Nr. : 60239-1-Ig
Synonyme
Geprüfte Anwendungen
Erfolgreiche Detektion in WB | HEK-293-Zellen, Raji-Zellen |
Erfolgreiche Detektion in IF-P | Mausherzgewebe, Rattenherzgewebe |
Empfohlene Verdünnung
Anwendung | Verdünnung |
---|---|
Western Blot (WB) | WB : 1:1000-1:4000 |
Immunfluoreszenz (IF)-P | IF-P : 1:200-1:800 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, check data in validation data gallery |
Veröffentlichte Anwendungen
WB | See 4 publications below |
IF | See 1 publications below |
Produktinformation
60239-1-Ig bindet in WB, IF-P, ELISA Desmocollin 2 und zeigt Reaktivität mit human, Maus, Ratten
Getestete Reaktivität | human, Maus, Ratte |
In Publikationen genannte Reaktivität | human |
Wirt / Isotyp | Maus / IgG2a |
Klonalität | Monoklonal |
Typ | Antikörper |
Immunogen | Desmocollin 2 fusion protein Ag5450 |
Vollständiger Name | desmocollin 2 |
Berechnetes Molekulargewicht | 100 kDa |
Beobachtetes Molekulargewicht | 110 kDa |
GenBank-Zugangsnummer | BC063291 |
Gene symbol | Desmocollin 2 |
Gene ID (NCBI) | 1824 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS with 0.02% sodium azide and 50% glycerol |
Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Desmocollin 2 (DSC2) is a member of the desmocollin subfamily of the cadherin superfamily. The desmocollins (DSC1-3), along with the desmogleins (DSG1-4), are found primarily in epithelia and cardiac muscle where they constitute the adhesive proteins of the intercellular desmosome junctions and are required for cell adhesion and desmosome formation. Mutations in DSC2 gene are associated with arrhythmogenic right ventricular dysplasia-11.
Protokolle
PRODUKTSPEZIFISCHE PROTOKOLLE | |
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WB protocol for Desmocollin 2 antibody 60239-1-Ig | Protokoll herunterladen |
IF protocol for Desmocollin 2 antibody 60239-1-Ig | Protokoll herunterladen |
STANDARD-PROTOKOLLE | |
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Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |
Publikationen
Species | Application | Title |
---|---|---|
J Cell Biol DPM1 modulates desmosomal adhesion and epidermal differentiation through SERPINB5 | ||
Acta Physiol (Oxf) Clustering of desmosomal cadherins by desmoplakin is essential for cell-cell adhesion. | ||
PLoS Pathog Porphyromonas gingivalis induces penetration of lipopolysaccharide and peptidoglycan through the gingival epithelium via degradation of junctional adhesion molecule 1. | ||
Stem Cell Res Ther Both Wnt signaling and epidermal stem cell-derived extracellular vesicles are involved in epidermal cell growth. | ||
Mol Ther Oncolytics Exosomal miR-205-5p enhances angiogenesis and nasopharyngeal carcinoma metastasis by targeting desmocollin-2. | ||
Heliyon The role of FERMT2 in the tumor microenvironment and immunotherapy in pan-cancer using comprehensive single-cell and bulk sequencing |
Rezensionen
The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.
FH Jane (Verified Customer) (02-03-2022) | A very weak and smear band found around the right molecular weight. However, the quality is not good enough to do any analysis or generate results.
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FH Jing (Verified Customer) (02-04-2020) | Tested in hiPSC-derived cardiomyocytes, it showed band around 130Kd.
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