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DSCAML1 Polyklonaler Antikörper

DSCAML1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32634-1-PBS

Synonyme

Cell adhesion molecule DSCAML1, Down syndrome cell adhesion molecule 2, Down syndrome cell adhesion molecule-like protein 1, DSCAM2, KIAA1132

Filter:
  • Western Blot (WB) analysis of various lysates using DSCAML1 Polyclonal antibody (32634-1-AP)

    WB analysis using 32634-1-AP (same clone as 32634-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32634-1-AP (DSCAML1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32634-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32634-1-PBS bindet in WB, Indirect ELISA DSCAML1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen DSCAML1 fusion protein Ag36336
Vollständiger Name Down syndrome cell adhesion molecule like 1
Berechnetes Molekulargewicht224 kDa
Beobachtetes Molekulargewicht224 kDa
GenBank-ZugangsnummerNM_020693
Gene symbol DSCAML1
Gene ID (NCBI) 57453
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Down syndrome cell adhesion molecule-like protein 1 (DSCAML1) is a transmembrane protein with ten immunoglobulin (Ig) and six fibronectin type III domains (PMID: 11453658). It is involved in neuronal cell adhesion and plays a crucial role in the development and function of the nervous system. DSCAML1 has been shown to participate in neuronal tiling, avoidance of neurite fasciculation, and axon guidance (PMID: 18216855; 21029858). Additionally, DSCAML1 is required for the proper placement of GABAergic neurons in the entorhinal cortex (ECx) and suppression of seizure susceptibility in rodents (PMID: 33256836).