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DUPD1 / DUSP27 Polyklonaler Antikörper

DUPD1 / DUSP27 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25259-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using DUPD1 / DUSP27 Polyclonal antibody (25259-1-AP)

    WB analysis using 25259-1-AP (same clone as 25259-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25259-1-AP (DUPD1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25259-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

25259-1-PBS bindet in WB, Indirect ELISA DUPD1 / DUSP27 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen DUPD1 / DUSP27 fusion protein Ag19658
Vollständiger Name dual specificity phosphatase and pro isomerase domain containing 1
Berechnetes Molekulargewicht 220 aa, 25 kDa
Beobachtetes Molekulargewicht27 kDa
GenBank-ZugangsnummerBC137322
Gene symbol DUSP27
Gene ID (NCBI) 338599
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Dupd1also named as Dusp27, has been categorized as an atypical dual-specificity phosphatase (Dusp) capable of dephosphorylating both tyrosine and serine/threonine residues. It's involved in the modulation of intracellular signaling cascades. In skeletal muscle Dupd1 regulates systemic glucose homeostasis by activating AMPK, which is an energy sensor protein kinase. Dupd1 also affects MAP kinase signaling though modulation of the MAPK1/2 cascade in skeletal muscle promoting muscle cell differentiation, development and atrophy.