DUSP12 Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

DUSP12 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 15667-1-PBS

Synonyme

---

• 

  WB analysis of HeLa using 15667-1-AP (same clone as 15667-1-PBS)

  WB result of DUSP12 antibody (15667-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-DUSP12 transfected HeLa cells. This data was developed using the same antibody clone with 15667-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 15667-1-AP (same clone as 15667-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 15667-1-AP (DUSP12 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15667-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse kidney using 15667-1-AP (same clone as 15667-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 15667-1-AP (DUSP12 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15667-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse embryo using 15667-1-AP (same clone as 15667-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse embryo tissue slide using 15667-1-AP (DUSP12 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15667-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

15667-1-PBS bindet in WB, IHC, Indirect ELISA DUSP12 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: DUSP12 fusion protein Ag8131
• Vollständiger Name: dual specificity phosphatase 12
• Berechnetes Molekulargewicht: 370 aa, 43 kDa
• Beobachtetes Molekulargewicht: 35 kDa
• GenBank-Zugangsnummer: BC006286
• Gene symbol: DUSP12
• Gene ID (NCBI): 11266
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DUSP12 (Dual specificity protein phosphatase 12) belongs to the protein-tyrosine phosphatase family and non-receptor class dual specificity subfamily. DUSP12 is a kind of dual specificity phosphatase. It can dephosphorylate both phosphotyrosine and phosphoserine or phosphothreonine residues and can dephosphorylate glucokinase in vitro (PMID:10446167). In addition, DUSP12 has phosphatase activity with the synthetic substrate 6,8-difluoro-4-methylumbelliferyl phosphate and other in vitro substrates (PMID:24531476). DUSP12 is ubiquitously expressed in spleen, testis, ovary, and peripheral blood leukocytes and lower expression in liver and lung.