DUSP19 Rekombinanter Antikörper

DUSP19 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

251021A12

Kat-Nr. : 86354-1-RR

Synonyme

Dual specificity phosphatase TS-DSP1, DUSP17, EC:3.1.3.16, LMW DSP3, LMWDSP3

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  WB analysis using 86354-1-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 86354-1-RR (DUSP19 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse pancreas using 86354-1-RR

  mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 86354-1-RR (DUSP19 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 86354-1-RR

  Biolayer interferometry (BLl) kinetic assays of 86354-1-RR against Human DUSP19 were performed. The affinity constant is below 1 pM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: U2OS-Zellen, HepG2-Zellen, HuH-7-Zellen, Maus-Pankreasgewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

86354-1-RR bindet in WB, ELISA DUSP19 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: DUSP19 fusion protein Ag3611
• Vollständiger Name: dual specificity phosphatase 19
• Berechnetes Molekulargewicht: 217 aa, 24 kDa
• Beobachtetes Molekulargewicht: 26 kDa
• GenBank-Zugangsnummer: BC035000
• Gene symbol: DUSP19
• Gene ID (NCBI): 142679
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DUSP19 (Dual-Specificity Phosphatase 19), also known as SKRP1, LMW-DSP3, or SAPK pathway-regulating phosphatase 1, is a low-molecular-weight member of the dual-specificity phosphatase family. It is encoded on human chromosome 2q32 and expressed in multiple tissues, with the highest levels found in the pancreas and heart. Structurally, DUSP19 contains a conserved catalytic domain that removes phosphate groups from both phospho-tyrosine and phospho-serine/threonine residues, enabling it to negatively or positively regulate MAPK signaling.