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DUSP2 Polyklonaler Antikörper

DUSP2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27327-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of A549 cells using DUSP2 Polyclonal antibody (27327-1-AP)

    WB analysis of A549 using 27327-1-AP (same clone as 27327-1-PBS)

    A549 cells were subjected to SDS PAGE followed by western blot with 27327-1-AP (DUSP2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27327-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using DUSP2 Polyclonal antibody (27327-1-AP)

    WB analysis using 27327-1-AP (same clone as 27327-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27327-1-AP (DUSP2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27327-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HeLa cells using DUSP2 Polyclonal antibody (27327-1-AP)

    WB analysis of HeLa using 27327-1-AP (same clone as 27327-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 27327-1-AP (DUSP2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27327-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27327-1-PBS bindet in WB, Indirect ELISA DUSP2 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen DUSP2 fusion protein Ag25380
Vollständiger Name dual specificity phosphatase 2
Berechnetes Molekulargewicht 34 kDa
Beobachtetes Molekulargewicht 34 kDa
GenBank-ZugangsnummerBC007771
Gene symbol DUSP2
Gene ID (NCBI) 1844
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DUSP2 belongs to the sub-family of nuclear specific DUSPs that includes DUSP1, 4 and 5. DUSP2 is highly expressed in immune cells, in particular, of patients with inflammatory arthritis, such as in rheumatoid arthritis (RA), and Dusp2 knockout mice present a significant reduction in inflammatory responses. It has been demonstrated that DUSP2 is a downstream target of the tumor suppressor p53 that is required for the cellular response to oxidative stress. DUSP2 is also involved in transcription factor E2F1-mediated apoptotic signaling. Like other members of the DUSP family, DUSP2 interacts with MAPKs; However, the target protein for its phosphatase activity is controversial.