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DUSP5 Polyklonaler Antikörper

DUSP5 Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30256-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using DUSP5 Polyclonal antibody (30256-1-AP)

    WB analysis using 30256-1-AP (same clone as 30256-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30256-1-AP (DUSP5 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30256-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of A549 cells using DUSP5 Polyclonal antibody (30256-1-AP)

    IP experiment of A549 using 30256-1-AP (same clone as 30256-1-PBS)

    IP result of anti-DUSP5 (IP:30256-1-AP, 4ug; Detection:30256-1-AP 1:500) with A549 cells lysate 1200 ug. This data was developed using the same antibody clone with 30256-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30256-1-PBS bindet in WB, IP, Indirect ELISA DUSP5 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen DUSP5 fusion protein Ag32997
Vollständiger Name dual specificity phosphatase 5
Berechnetes Molekulargewicht42kd
Beobachtetes Molekulargewicht 42 kDa
GenBank-ZugangsnummerNM_004419
Gene symbol DUSP5
Gene ID (NCBI) 1847
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DUSP5 (Dual specificity protein phosphatase 5) is also named as VH3. DUSP5, a member of DUSPs superfamily, is located in the nucleus and plays crucially regulatory roles in the signaling pathway transduction (PMID: 34169608). DUSP5 promotes the osteogenic differentiation of mesenchymal stromal cells (MSCs) by repressing SMAD1 signaling pathway in a SCP1/2‐dependent manner (PMID: 34169608). DUSP5, which specifically dephosphorylates extracellular signal-regulated kinase (ERK1/2), blocks pulmonary vascular smooth muscle cell proliferation (PMID: 34142888). DUSP5, an ERK1/2-specific endogenous phosphatase, was expressed at low levels in CRC (PMID: 36526622). DUSP5, a member of the DUSP subfamily, is known to regulate cellular inflammation (PMID: 33361528).