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DYNC1H1 Rekombinanter Antikörper

DYNC1H1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242706B12

Kat-Nr. : 85397-4-PBS

Synonyme

DYNC1H 1

Filter:
  • Western Blot (WB) analysis of various lysates using DYNC1H1 Recombinant antibody (85397-4-RR)

    WB analysis using 85397-4-RR (same clone as 85397-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85397-4-RR (KIAA0325 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85397-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85397-4-PBS

    Affinity and Kinetic Characterization of 85397-4-PBS

    Biolayer interferometry (BLl) kinetic assays of 85397-4-RR against Human DYNC1H1 were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

85397-4-PBS bindet in WB, Indirect ELISA DYNC1H1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen DYNC1H1 fusion protein Ag2999
Vollständiger Name dynein, cytoplasmic 1, heavy chain 1
Berechnetes Molekulargewicht 4646 aa, 532 kDa
Beobachtetes Molekulargewicht532 kDa
GenBank-ZugangsnummerBC021297
Gene symbol DYNC1H1
Gene ID (NCBI) 1778
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Dyneins are a group of microtubule-activated ATPases that convert chemical energy into mechanical energy. It can be divided into 2 large subgroups, namely, the axonemal and cytoplasmic dyneins. The conventional cytoplasmic dynein comprises 2 heavy chain polypeptides and several intermediate and light chains. DYNC1H1 is a cytoplasmic dynein and belongs to the dynein heavy chain family. It acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. DYNC1H1 has been implicated in the degeneration of dopaminergic neuron axons and motor neurons in PD patients.