DYNC1LI2 Polyklonaler Antikörper

DYNC1LI2 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 18885-1-PBS

Synonyme

LIC53/55, LIC-2, LIC2, LIC 2, DNCLI2

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  WB analysis of mouse testis using 18885-1-AP (same clone as 18885-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 18885-1-AP (DYNC1LI2 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18885-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 18885-1-AP (same clone as 18885-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 18885-1-AP (DYNC1LI2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18885-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 18885-1-AP (same clone as 18885-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 18885-1-AP (DYNC1LI2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18885-1-PBS in a different storage buffer formulation.

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  IHC staining of rat kidney using 18885-1-AP (same clone as 18885-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 18885-1-AP (DYNC1LI2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18885-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat kidney using 18885-1-AP (same clone as 18885-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat kidney tissue slide using 18885-1-AP (DYNC1LI2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18885-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 18885-1-AP (same clone as 18885-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 18885-1-AP (DYNC1LI2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18885-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human placenta using 18885-1-AP (same clone as 18885-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 18885-1-AP (DYNC1LI2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18885-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

18885-1-PBS bindet in WB, IHC, Indirect ELISA DYNC1LI2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: DYNC1LI2 fusion protein Ag13452
• Vollständiger Name: dynein, cytoplasmic 1, light intermediate chain 2
• Berechnetes Molekulargewicht: 492 aa, 54 kDa
• Beobachtetes Molekulargewicht: 48-50 kDa
• GenBank-Zugangsnummer: BC025959
• Gene symbol: DYNC1LI2
• Gene ID (NCBI): 1783
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Cytoplasmic dynein is a microtubule-associated motor protein. DYNC1LI2 (Cytoplasmic dynein 1 light intermediate chain 2), also known as LIC2, belongs to the dynein light intermediate chain family. DYNC1LI2 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. It may play a role in binding dynein to membranous organelles or chromosomes. Northern blot analysis of rat tissues detected high expression of DYNC1LI2 in skeletal muscle, testis, heart, lung, and brain, and lower expression in liver, kidney, and spleen (PMID: 7738094).