DYRK1B Polyklonaler Antikörper

DYRK1B Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12240-1-PBS

Synonyme

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  WB analysis of mouse testis using 12240-1-AP (same clone as 12240-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 12240-1-AP (DYRK1B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12240-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse skeletal muscle using 12240-1-AP (same clone as 12240-1-PBS)

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 12240-1-AP (DYRK1B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12240-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human colon using 12240-1-AP (same clone as 12240-1-PBS)

  human colon tissue were subjected to SDS PAGE followed by western blot with 12240-1-AP (DYRK1B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12240-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human heart using 12240-1-AP (same clone as 12240-1-PBS)

  human heart tissue were subjected to SDS PAGE followed by western blot with 12240-1-AP (DYRK1B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12240-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HeLa using 12240-1-AP (same clone as 12240-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 12240-1-AP (DYRK1B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12240-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

12240-1-PBS bindet in WB, Indirect ELISA DYRK1B und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: DYRK1B fusion protein Ag2883
• Vollständiger Name: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
• Berechnetes Molekulargewicht: 629 aa, 69 kDa
• Beobachtetes Molekulargewicht: 57 kDa
• GenBank-Zugangsnummer: BC018751
• Gene symbol: DYRK1B
• Gene ID (NCBI): 9149
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

DYRK1B(dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B) is also named as MIRK. It is a member of the dyrk/minibrain family of serine/threonine kinases that mediate the transition from growth to differentiation in lower eukaryotes and mammals(PMID:15546868). DYRK1B functions as a transcriptional coactivator that is activated by co-expressed MKK3, a MAP kinase that also can activate p38 MAP kinase(PMID:14500717). The DYRK1B splice variants found in each muscle tissue exhibit approximate molecular weights of 70 and 75 kDa(PMID:12902328). It has 3 isoforms produced by alternative splicing of the molecular weight of 65-69 kDa.