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Destrin Polyklonaler Antikörper

Destrin Polyklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10962-2-PBS

Synonyme

DSTN, DSN, ADF, Actin-depolymerizing factor, ACTDP

Filter:
  • Western Blot (WB) analysis of various lysates using Destrin Polyclonal antibody (10962-2-AP)

    WB analysis using 10962-2-AP (same clone as 10962-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 10962-2-AP (Destrin antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10962-2-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human skin cancer tissue using Destrin Polyclonal antibody (10962-2-AP)

    IHC staining of human skin cancer using 10962-2-AP (same clone as 10962-2-PBS)

    Immunohistochemical analysis of paraffin-embedded skin cancer slide using 10962-2-AP (Destrin antibody) at dilution of 1:300 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10962-2-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of MCF-7 cells using Destrin Polyclonal antibody (10962-2-AP)

    IF Staining of MCF-7 using 10962-2-AP (same clone as 10962-2-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed MCF-7 cells using Destrin antibody (10962-2-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 10962-2-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

10962-2-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA Destrin und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Destrin fusion protein Ag1402
Vollständiger Name destrin (actin depolymerizing factor)
Berechnetes Molekulargewicht 19 kDa
Beobachtetes Molekulargewicht18 kDa
GenBank-ZugangsnummerBC009477
Gene symbol Destrin
Gene ID (NCBI) 11034
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Destrin (also known as actin depolymerization factor, ADF) is an actin-binding protein contributing to cytoskeletal dynamics by promoting rapid actin filament disassembly. By regulating actin cytoskeletal reorganization it plays an important role in the formation of filopodia, which further promotes tumor cell invasion and metastasis. Destrin has been reported to be overexpressed in primary colon cancer.