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Dynamitin (1-401 AA) Monoklonaler Antikörper

Dynamitin (1-401 AA) Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG3

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2B9A5

Kat-Nr. : 60257-1-PBS

Synonyme

DCTN 50, DCTN2, DCTN50, dynactin 2, dynactin 2 (p50), Dynactin subunit 2, Dynamitin, Dynamitin (1-401 AA), p50 dynamitin, RBP50

Filter:
  • Western Blot (WB) analysis of human brain tissue using Dynamitin (1-401 AA) Monoclonal antibody (60257-1-Ig)

    WB analysis of human brain using 60257-1-Ig (same clone as 60257-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 60257-1-Ig (Dynamitin antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60257-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human gliomas tissue using Dynamitin (1-401 AA) Monoclonal antibody (60257-1-Ig)

    IHC staining of human gliomas using 60257-1-Ig (same clone as 60257-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human gliomas slide using 60257-1-Ig (Dynamitin antibody at dilution of 1:50. This data was developed using the same antibody clone with 60257-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human gliomas tissue using Dynamitin (1-401 AA) Monoclonal antibody (60257-1-Ig)

    IHC staining of human gliomas using 60257-1-Ig (same clone as 60257-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human gliomas slide using 60257-1-Ig (Dynamitin antibody at dilution of 1:50. This data was developed using the same antibody clone with 60257-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

60257-1-PBS bindet in WB, IHC, Indirect ELISA Dynamitin (1-401 AA) und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Maus / IgG3
Klonalität Monoklonal
Typ Antikörper
Immunogen Dynamitin (1-401 AA) fusion protein Ag1902
Vollständiger Name dynactin 2 (p50)
Berechnetes Molekulargewicht 401 aa, 44 kDa
Beobachtetes Molekulargewicht 52+150 kDa
GenBank-ZugangsnummerBC014083
Gene symbol Dynamitin
Gene ID (NCBI) 10540
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Dynamitin is a 50 kDa protein containing a calmodulin binding domain, a putative ATPase domain and MacMARCKS-binding domain. This protein is a part of the dynactin complex believed to link the dynactin complex to membrane compartments. Its functions are tightly associated with dynein motor protein, thus extend to vesicle trafficking and membrane integrity. Dynamitin was named so because its overexpression causes dynactin complex which contains 10 subunits, to disassemble. Its N terminal 58 amino acid is for MacMARCKS binding and residues 59-83 is responsible for calmodulin binding. This antibody is is against the N terminal 86aa of full length p50 dynamitin.