Dysbindin Polyklonaler Antikörper

Dysbindin Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11132-1-PBS

Synonyme

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  WB analysis of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 11132-1-AP (Dysbindin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11132-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse testis using 11132-1-AP (same clone as 11132-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 11132-1-AP (Dysbindin antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11132-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human testis using 11132-1-AP (same clone as 11132-1-PBS)

  human testis tissue were subjected to SDS PAGE followed by western blot with 11132-1-AP (Dysbindin antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11132-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11132-1-AP (Dysbindin antibody at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11132-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 11132-1-AP (same clone as 11132-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 11132-1-AP (Dysbindin antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11132-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

11132-1-PBS bindet in WB, IHC, Indirect ELISA Dysbindin und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Dysbindin fusion protein Ag1613
• Vollständiger Name: dystrobrevin binding protein 1
• Berechnetes Molekulargewicht: 351 aa, 39 kDa
• Beobachtetes Molekulargewicht: 48 kDa, 36 kDa
• GenBank-Zugangsnummer: BC011912
• Gene symbol: Dysbindin
• Gene ID (NCBI): 84062
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Dysbindin, encoded by DTNBP1 (dystrobrevin binding protein 1), is a synaptic protein which is expressed in diverse neuronal populations throughout the brain. Genetic variation in DTNBP1 is associated with schizophrenia. Reduced expression of dysbindin has been reported in the dorsolateral prefrontal cortex (DLPFC) of schizophrenia cases. Several isoforms of dysbindin exist: 48-50 kDa of dysbindin-1A, 35-38 kDa of dysbindin-1B, and 30-32 kDa of dysbindin-1C. This antibody recognizes all of isoforms of dysbindin. (19617633)