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E2F6 Polyklonaler Antikörper

E2F6 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10691-1-PBS

Synonyme

E2F-6, E2F 6

Filter:
  • Western Blot (WB) analysis of various lysates using E2F6 Polyclonal antibody (10691-1-AP)

    WB analysis using 10691-1-AP (same clone as 10691-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 10691-1-AP (E2F6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10691-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

10691-1-PBS bindet in WB, Indirect ELISA E2F6 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen E2F6 fusion protein Ag1029
Vollständiger Name E2F transcription factor 6
Berechnetes Molekulargewicht 32 kDa
Beobachtetes Molekulargewicht37 kDa
GenBank-ZugangsnummerBC008348
Gene symbol E2F6
Gene ID (NCBI) 1876
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

E2F6 is a member of the E2F family of transcription factors, which play important roles in cell cycle regulation and gene expression. E2F6 is highly expressed in many types of cancer and is associated with poor prognosis. It is involved in the regulation of cell proliferation and can promote tumor growth. E2F6 knockdown significantly reduces the proliferative ability of glioma cells (PMID: 38071912). Additionally, E2F6 is related to immune activation markers, tumor immune cell infiltration, and immune regulators, making it a potential biomarker for predicting the response to cancer immunotherapy.