EDARADD Polyklonaler Antikörper

EDARADD Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32485-1-PBS

Synonyme

Ectodysplasin-A receptor-associated adapter protein, EDAR-associated death domain protein, Protein crinkled homolog

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  WB analysis using 32485-1-AP (same clone as 32485-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32485-1-AP (EDARADD antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32485-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

32485-1-PBS bindet in WB, Indirect ELISA EDARADD und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: EDARADD fusion protein Ag38064
• Vollständiger Name: EDAR-associated death domain
• Beobachtetes Molekulargewicht: 24 kDa
• GenBank-Zugangsnummer: BC128082
• Gene symbol: EDARADD
• Gene ID (NCBI): 128178
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

EDARADD (EDAR-associated death domain) is an adaptor protein that mediates the interaction between the extracellular Ectodysplasin A receptor (EDAR) and intracellular signaling components, orchestrating a series of downstream events that regulate key biological processes such as cell proliferation, differentiation, and apoptosis. EDARADD is a 25 KDa death domain-containing adaptor protein. EDARADD was shown to interact with TRAF1, -2 and -3 as well as with TAB2 (TAK1-binding protein 2) and is therefore likely to be responsible for coupling receptor activation with engagement of the NF-κB pathway (PMID: 23845861).