EFCAB1 Polyklonaler Antikörper

EFCAB1 Polyklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

Publikationen(1)

Kat-Nr. : 17276-1-AP

Synonyme

EF-hand calcium-binding domain-containing protein 1, CLXN, Calaxin

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  IHC staining of human colon using 17276-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 17276-1-AP (EFCAB1 antibody) at dilution of 1:200 (under 10x lens).

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  IHC staining of human colon using 17276-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 17276-1-AP (EFCAB1 antibody) at dilution of 1:200 (under 40x lens).

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  IHC staining of mouse testis using 17276-1-AP

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 17276-1-AP (EFCAB1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of mouse testis using 17276-1-AP

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 17276-1-AP (EFCAB1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human liver using 17276-1-AP

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 17276-1-AP (EFCAB1 antibody) at dilution of 1:200 (under 10x lens).

• 

  IHC staining of human liver using 17276-1-AP

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 17276-1-AP (EFCAB1 antibody) at dilution of 1:200 (under 40x lens).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IHC: humanes Kolongewebe, humanes Lebergewebe, Maushodengewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

• Immunhistochemie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 1 publications below

Produktinformation

17276-1-AP bindet in WB, IHC, ELISA EFCAB1 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: EFCAB1 fusion protein Ag11039
• Vollständiger Name: EF-hand calcium binding domain 1
• Berechnetes Molekulargewicht: 211 aa, 24 kDa
• GenBank-Zugangsnummer: BC025676
• Gene symbol: EFCAB1
• Gene ID (NCBI): 79645
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

EFCAB1, also known as Calaxin, is a gene that encodes a protein involved in the function of cilia and flagella, which are hair-like structures protruding from the surface of certain cells. Research indicates that EFCAB1 overexpression inhibits cell proliferation, migration, and invasion while promoting apoptosis in lung adenocarcinoma cells. This suggests that EFCAB1 could potentially serve as a biomarker for lung adenocarcinoma.

Publikationen

Species	Application	Title
human	WB	Andrology; A novel homozygous LRRC6 mutation causes male infertility with asthenozoospermia and primary ciliary dyskinesia in humans; Authors - Shengjia Shi