EFCAB4A Polyklonaler Antikörper

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• KD/KO Validated

EFCAB4A Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32115-1-PBS

Synonyme

Ca2+ Release-Activated Ca2+ (CRAC) Channel Regulator 2B, Calcium Release Activated Channel Regulator 2B, Calcium release-activated calcium channel regulator 2B, Calcium release-activated channel regulator 2B, CRAC channel regulator 2B

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  WB analysis using 32115-1-AP (same clone as 32115-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32115-1-AP (EFCAB4A antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32115-1-PBS in a different storage buffer formulation.

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  WB analysis of LNCaP using 32115-1-AP (same clone as 32115-1-PBS)

  WB result of EFCAB4A antibody (32115-1-AP; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-EFCAB4A transfected LNCaP cells. This data was developed using the same antibody clone with 32115-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

32115-1-PBS bindet in WB, Indirect ELISA EFCAB4A und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: EFCAB4A fusion protein Ag37031
• Vollständiger Name: EF-hand calcium binding domain 4A
• Beobachtetes Molekulargewicht: 50 kDa
• GenBank-Zugangsnummer: BC033196
• Gene symbol: EFCAB4A
• Gene ID (NCBI): 283229
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

EFCAB4A (EF-hand calcium-binding domain-containing protein 4A), also known as CRACR2B (calcium release-activated calcium channel regulator 2B), is a calcium-binding protein containing EF-hand structural domain. EFCAB4A is thought to play a key role in calcium bank-manipulated calcium endocytosis (SOCE) in T cells by regulating activation of CRAC (calcium release-activated calcium channel) channels. This protein may perform a similar function to EFCAB4B, which acts as a cytoplasmic calcium sensor that forms a complex with ORAI1 and STIM1 in the region of the junction between the endoplasmic reticulum and the plasma membrane. The EFCAB4A protein contains two EF-hand structural domains, which may be involved in calcium bank-manipulated calcium endocytosis.