EHD2 Rekombinanter Antikörper
EHD2 Rekombinant Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
243038C6
Kat-Nr. : 85604-4-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
85604-4-PBS bindet in WB, Indirect ELISA EHD2 und zeigt Reaktivität mit human, Maus, Ratten
Getestete Reaktivität | human, Maus, Ratte |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Rekombinant |
Typ | Antikörper |
Immunogen | EHD2 fusion protein Ag2002 |
Vollständiger Name | EH-domain containing 2 |
Berechnetes Molekulargewicht | 543 aa, 61 kDa |
Beobachtetes Molekulargewicht | 61 kDa |
GenBank-Zugangsnummer | BC014445 |
Gene symbol | EHD2 |
Gene ID (NCBI) | 30846 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Protein-A-Reinigung |
Lagerungspuffer | PBS only |
Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
EH domain-containing protein 2 (EHD2) is a member of the EHD protein family. It is primarily located in the plasma membrane but can also be found in the cytoplasm and endosomes. EHD2 is also a nuclear-cytoplasmic shuttle protein, acting as a corepressor of transcription to inhibit gene transcription when it enters the cell nucleus. EHD2 is a dynamin-related ATPase that plays a key role in regulating a series of biological processes. As a crucial regulator of endocytic transport, it is involved in the formation and maintenance of endosomal tubules and vesicles, which are vital for intracellular transport of proteins and other substances. EHD2 has been implicated in several human cancers and has potential as a predictive biomarker of chemotherapy efficacy.