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EIF3H Polyklonaler Antikörper

EIF3H Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11310-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using EIF3H Polyclonal antibody (11310-1-AP)

    WB analysis using 11310-1-AP (same clone as 11310-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11310-1-AP (EIF3H antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11310-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

11310-1-PBS bindet in WB, Indirect ELISA EIF3H und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen EIF3H fusion protein Ag1850
Vollständiger Name eukaryotic translation initiation factor 3, subunit H
Berechnetes Molekulargewicht 40 kDa
Beobachtetes Molekulargewicht 40 kDa
GenBank-ZugangsnummerBC000386
Gene symbol EIF3H
Gene ID (NCBI) 8667
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Eukaryotic translation initiation factor eIF3, that plays a central role in translation initiation, consists of five core subunits that are present in both the budding yeast and higher eukaryotes. The EIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex. The complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. It is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. EIF3H is a component of the EIF3 complex. [PMID:19204574,20503360]