EIF3I Rekombinanter Antikörper
EIF3I Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus
Anwendung
WB, Cytometric bead array, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
243040B3
Kat-Nr. : 85603-2-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
85603-2-PBS bindet in WB, Cytometric bead array, Indirect ELISA EIF3I und zeigt Reaktivität mit human, Maus
| Getestete Reaktivität | human, Maus |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Rekombinant |
| Typ | Antikörper |
| Immunogen | EIF3I fusion protein Ag1847 |
| Vollständiger Name | eukaryotic translation initiation factor 3, subunit I |
| Berechnetes Molekulargewicht | 36 kDa |
| Beobachtetes Molekulargewicht | 36 kDa |
| GenBank-Zugangsnummer | BC000413 |
| Gene symbol | EIF3I |
| Gene ID (NCBI) | 8668 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Eukaryotic initiation factor (EIF3) complex is the largest of the eIFs and consists of more than 10 nonidentical subunit, and is required for several steps in the initiation of protein synthesis. It associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). Also it can stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. EIF3I is one subunit of EIF3 complex.





