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ELAVL2 Rekombinanter Antikörper

ELAVL2 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251573E1

Kat-Nr. : 86623-3-PBS

Synonyme

ELAV2, ELAVL 2, ELAV-like neuronal protein 1, ELAV-like protein 2, Hu-antigen B

Filter:
  • Western Blot (WB) analysis of various lysates using ELAVL2 Recombinant monoclonal antibody (86623-3-RR)

    WB analysis using 86623-3-RR (same clone as 86623-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86623-3-RR (ELAVL2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86623-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86623-3-RR

    Affinity and Kinetic Characterization of 86623-3-RR

    Biolayer interferometry (BLl) kinetic assays of 86623-3-RR against Human ELAVL2 were performed. The affinity constant is 0.424 nM.

Geprüfte Anwendungen

Produktinformation

86623-3-PBS bindet in WB, Indirect ELISA ELAVL2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen ELAVL2 fusion protein Ag5105
Vollständiger Name ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
Berechnetes Molekulargewicht 39 kDa
Beobachtetes Molekulargewicht39 kDa
GenBank-ZugangsnummerBC030692
Gene symbol ELAVL2
Gene ID (NCBI) 1993
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The ELAV (embryonic lethal abnormal visual system) gene of D. Melanogaste is the the first identified member of a family of neuronal RNA binding proteins that is conserved in metazoans. The proteins in this family contain three RNA Recognition Motifs (RRM), with a hinge region separating the second and third RRMs and an optional non-conserved N-terminal region. The hinge includes signals essential for nuclear export and subcellular localization [PMID:9874760]. Elav is expressed specifically in the neurons and is required for the correct development and maintenance of the nervous system. ELAVL2 can binds RNA, and recognize a GAAA motif. In addition, it can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.