ELL2 Polyklonaler Antikörper

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• KD/KO Validated

ELL2 Polyklonal Antikörper für WB, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12727-1-PBS

Synonyme

ELL 2

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  WB analysis using 12727-1-AP (same clone as 12727-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12727-1-AP (ELL2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12727-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 12727-1-AP (same clone as 12727-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12727-1-AP (ELL2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12727-1-PBS in a different storage buffer formulation.

• 

  IP experiment of mouse brain using 12727-1-AP (same clone as 12727-1-PBS)

  IP result of anti-ELL2 (IP:12727-1-AP, 4ug; Detection:12727-1-AP 1:300) with mouse brain tissue lysate 3440ug. This data was developed using the same antibody clone with 12727-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

12727-1-PBS bindet in WB, IP, Indirect ELISA ELL2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: ELL2 fusion protein Ag3428
• Vollständiger Name: elongation factor, RNA polymerase II, 2
• Berechnetes Molekulargewicht: 640 aa, 72 kDa
• Beobachtetes Molekulargewicht: 72 kDa
• GenBank-Zugangsnummer: BC028412
• Gene symbol: ELL2
• Gene ID (NCBI): 22936
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ELL2 (Elongation Factor for RNA Polymerase II 2) is a key transcriptional elongation factor that regulates RNA polymerase II (Pol II) during mRNA synthesis (PMID: 34265249). It belongs to the ELL gene family, which includes ELL1, ELL2, and ELL3, and plays a crucial role in controlling the elongation phase of transcription (PMID: 9108030). ELL2 is an androgen-responsive gene that is expressed by prostate epithelial cells and is frequently down-regulated in prostate cancer (PMID: 29179998).