EMCN Polyklonaler Antikörper

EMCN Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus und mehr (1)

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(3)

Kat-Nr. : 11828-1-AP

Synonyme

MUC-14, MUC14, Gastric cancer antigen Ga34, Endomucin-2, Endomucin

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  WB analysis using 11828-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 11828-1-AP (EMCN antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Mausherzgewebe, Mausnierengewebe, Mauslungengewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• IHC: See 1 publications below
• IF: See 2 publications below

Produktinformation

11828-1-AP bindet in WB, IHC, IF, ELISA EMCN und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: EMCN fusion protein Ag2396
• Vollständiger Name: endomucin
• Berechnetes Molekulargewicht: 19 kDa, 27 kDa
• Beobachtetes Molekulargewicht: 85 kDa
• GenBank-Zugangsnummer: BC017781
• Gene symbol: EMCN
• Gene ID (NCBI): 51705
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Endomucin (EMCN), also known as Endomucin 2 or Mucin 14, is a type I integral membrane glycoprotein that is endothelial-specific. EMCN is expressed on the surface of capillaries and venous and is highly expressed in highly vascularized tissues such as heart, kidney and lung (PMID: 29215001). Endomucin plays an important role in cell interaction, molecular cell signaling, angiogenesis and cell migration (PMID: 33532708). Since it is glycosylated, the apparent molecular weight of EMCN could be variable, ranging from 80 kDa to 120 kDa.

Publikationen

Species	Application	Title
rat	IHC	BMC Musculoskelet Disord; Transcutaneous CO2 application combined with low-intensity pulsed ultrasound accelerates bone fracture healing in rats; Authors - Kenichi Sawauchi
rat	IF	J Control Release; Injectable mineralized hydrogel microspheres for accelerated osteocyte network reconstruction and intelligent bone regeneration; Authors - Pengcheng Xiao
rat	IF	J Cell Mol Med; Sodium Hyaluronate-PDGF Repairs Cartilage and Subchondral Bone Microenvironment via HIF-1α-VEGF-Notch and SDF-1-CXCR4 Inhibition in Osteoarthritis; Authors - Zhengchao Wang