EML1 Polyklonaler Antikörper

EML1 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12765-1-PBS

Synonyme

HuEMAP-1, EMAP-1, EMAP, Echinoderm microtubule-associated protein-like 1

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  WB analysis using 12765-1-AP (same clone as 12765-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12765-1-AP (EML1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12765-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse brain using 12765-1-AP (same clone as 12765-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 12765-1-AP (EML1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12765-1-PBS in a different storage buffer formulation.

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  IHC staining of human intrahepatic cholangiocarcinoma using 12765-1-AP (same clone as 12765-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human intrahepatic cholangiocarcinoma tissue slide using 12765-1-AP (EML1 antibody) at dilution of 1:50 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12765-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach using 12765-1-AP (same clone as 12765-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 12765-1-AP (EML1 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12765-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

12765-1-PBS bindet in WB, IHC, Indirect ELISA EML1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: EML1 fusion protein Ag3429
• Vollständiger Name: echinoderm microtubule associated protein like 1
• Berechnetes Molekulargewicht: 815 aa, 90 kDa
• Beobachtetes Molekulargewicht: 90-92 kDa
• GenBank-Zugangsnummer: BC033043
• Gene symbol: EML1
• Gene ID (NCBI): 2009
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

EML1 is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type. The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems. The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3). The type I is the most severe form. Gene loci responsible for these three types are all mapped.