Endoglin/CD105 Monoklonaler Antikörper

Endoglin/CD105 Monoklonal Antikörper für Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3D9G5

Kat-Nr. : 68748-1-PBS

Synonyme

CD105, 3D9G5, HHT1, ENG, Endoglin

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  Cytometric bead array standard curve of MP50103-1

  Cytometric bead array standard curve of MP50103-1, ENG Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68748-1-PBS. Detection antibody: 68748-2-PBS. Standard:Eg0587. Range: 0.391-100 ng/mL.

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Geprüfte Anwendungen

Produktinformation

68748-1-PBS bindet in Cytometric bead array, Indirect ELISA Endoglin/CD105 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: endoglin
• Berechnetes Molekulargewicht: 71 kDa
• GenBank-Zugangsnummer: BC014271
• Gene symbol: CD105
• Gene ID (NCBI): 2022
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)