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Endoglin/CD105 Monoklonaler Antikörper

Endoglin/CD105 Monoklonal Antikörper für IF/ICC, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

IF/ICC, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2D4A5

Kat-Nr. : 68748-2-PBS

Synonyme

CD105, 2D4A5, HHT1, ENG, Endoglin

Filter:
  • Immunofluorescence (IF) / fluorescent staining of HUVEC cells using Endoglin/CD105 Monoclonal antibody (68748-2-Ig)

    IF Staining of HUVEC using 68748-2-Ig (same clone as 68748-2-PBS)

    Immunofluorescent analysis of un-fixed HUVEC cells using Endoglin/CD105 antibody (68748-2-Ig, Clone: 2D4A5 ) at dilution of 1:1422 and Multi-rAb CoraLite® Plus 594-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (Cat.NO. RGAM004 ). This data was developed using the same antibody clone with 68748-2-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP50103-1

    Cytometric bead array standard curve of MP50103-1

    Cytometric bead array standard curve of MP50103-1, ENG Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68748-1-PBS. Detection antibody: 68748-2-PBS. Standard:Eg0587. Range: 0.391-100 ng/mL.

Geprüfte Anwendungen

Produktinformation

68748-2-PBS bindet in IF/ICC, Cytometric bead array, Indirect ELISA Endoglin/CD105 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen Rekombinantes Protein
Vollständiger Name endoglin
Berechnetes Molekulargewicht 71 kDa
GenBank-ZugangsnummerBC014271
Gene symbol CD105
Gene ID (NCBI) 2022
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis. (PMID: 1326540; 14528280; 21737653; 12773481)