ENO3 Monoklonaler Antikörper
ENO3 Monoklonal Antikörper für WB, IF/ICC, Indirect ELISA
Wirt / Isotyp
Maus / IgG2b
Getestete Reaktivität
Hausschwein, human, Maus, Ratte
Anwendung
WB, IF/ICC, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
2C12G3
Kat-Nr. : 68147-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
68147-1-PBS bindet in WB, IF/ICC, Indirect ELISA ENO3 und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten
| Getestete Reaktivität | Hausschwein, human, Maus, Ratte |
| Wirt / Isotyp | Maus / IgG2b |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | ENO3 fusion protein Ag9642 |
| Vollständiger Name | enolase 3 (beta, muscle) |
| Berechnetes Molekulargewicht | 434 aa, 47 kDa |
| Beobachtetes Molekulargewicht | 42-47 kDa |
| GenBank-Zugangsnummer | BC017249 |
| Gene symbol | ENO3 |
| Gene ID (NCBI) | 2027 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Enolase 3 (ENO3) encodes the β-subunit of enolase, which is distributed in various tissues, including liver, lung, skeletal, and heart. ENO3 plays an important role in both glycogen and cholesterol metabolism. It has been demonstrated that ENO3 deficiency may lead to metabolic myopathies, and ENO3 speeds up hepatic cholesterol ester cumulation induced via the mediation of cholesteryl ester generation.Apart from these, ENO3 has also been involved in various tumors, though the results are contradictory. For example, ENO3 is up-regulated in STK11 mutant pulmonary carcinoma and colorectal carcinoma, while down-regulated in pancreatic cancer and hepatocellular carcinomas. ENO3 has 3 isoforms with the molecular mass of 42-47 kDa. (PMID: 33987359, 35004693)



