ENPP7 Polyklonaler Antikörper

ENPP7 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32226-1-PBS

Synonyme

Alkaline sphingomyelin phosphodiesterase, Alk-SMase, EC:3.1.4.12, Ectonucleotide pyrophosphatase/phosphodiesterase family member 7, E-NPP 7

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  WB analysis using 32226-1-AP (same clone as 32226-1-PBS)

  Mouse testis tissue lysate was subjected to SDS PAGE followed by western blot with 32226-1-AP (ENPP7 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32226-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

32226-1-PBS bindet in WB, Indirect ELISA ENPP7 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: ENPP7 fusion protein Ag36493
• Vollständiger Name: ectonucleotide pyrophosphatase/phosphodiesterase 7
• Berechnetes Molekulargewicht: 51 kDa，458aa
• Beobachtetes Molekulargewicht: 51 kDa
• GenBank-Zugangsnummer: NM_178543.4
• Gene symbol: ENPP7
• Gene ID (NCBI): 339221
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (ENPP7) stands out as an alkaline sphingomyelinase that functions in the intestine to cleave sphingomyelin (SM) into ceramide and phosphocholine in a phospholipase C (PLC) -like manner and has been associated with hepatobiliary diseases. Reduced ENPP7 activity is detected in colorectal cancer and in familial adenomatous polyposis, suggesting a link between decreased SM metabolism and colon tumorigenesis (PMID: 22177013; 28292932).